I recommend using SFTP instead of plain FTP and a smaller part size when using a Synology device as the upload target. The part size depends on your downlink speed on the Internet connection hosting Synology. My rule of thumb is 8 MiB for every 10 full Mbps of stable downlink speed. If you have a 28 Mbps downlink, use a part size of 16 MiB. If you have a stable 100 Mbps downlink (e.g. via fiber) use a part size of 80 MiB.
The most critical part, though, is making sure your Synology NAS is on-line at the time of the backup. Some ISPs do maintenance in the early hours, usually between 2am and 4am, when the network traffic is low. I've found out the hard way it's best to avoid uploading to a self-hosted NAS during those hours :)
Nicholas K. Dionysopoulos
Lead Developer and Director
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