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This message appears when Akeeba Backup detects that it cannot load its backup profile configuration. Usually, this means that something is going wrong with the database table itself. Sometime, it may mean that the backup profile is corrupt.

The easiest thing to test of the two is the latter.

Go to Components, Akeeba Backup for Joomla, Profile Managements.

Select the backup profile — I believe you only have one, profile #1.

Click on the Actions dropdown button on the toolbar.

Select Reset.

Now go back to Components, Akeeba Backup for Joomla.

If you are still getting the same message it means that one or more of the Akeeba Backup tables are corrupt. This is the kind of problem that Joomla's Database page cannot address when you click on that Fix button (Joomla can only try to fix the database schema, these are the fields defined in the table, not the database data which is what is broken when the table is corrupt).

Use your host-provided database tools to repair the tables with _akeebabackup_ in their names. If you do not know how to do that please ask your host; each host may have a different database administration interface and they know how to guide you through it.